Neuropathic pain is caused by disorders of, or damage to, the nervous system. The affected nerves can induce the sensation of pain in the brain. Neuropathic pain is often associated with the ...
Pain is one of the most debilitating symptoms that presents with neuropathy. Neuropathic pain syndrome is a challenge to treat and, even with appropriate evidence-based treatment, only a 40% ...
We are utilizing an oral NaV1.7 inhibitor for the potential treatment of neuropathic pain starting with Idiopathic Small Fiber neuropathy and Erythromelalgia, a novel eye drop formulation of a ...
Modulation of NaV1.7, therefore, should be an effective mechanism for decreasing pain. “Channel Therapeutics has chosen a three-pronged approach for our NaV1.7 molecule to demonstrate the utility of ...
XG005 is a non-opioid, new chemical entity with dual mode of action in targeting both nociceptive and neuropathic pain signals. The placebo, 750 mg or 1250 mg of XG005, was administered orally ...
“We are very pleased with the results, which potentially demonstrate that nerve blocks with our NaV1.7 inhibitors may be viable options for the treatment of acute and postoperative pain,” stated D ...