IL-6, STAT3 and NF-kB pathways were implicated in the TLR2 stimulated IL-17 and IL-23. Conclusions Our data demonstrate that TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and ...

IL-6. The release of these inflammation-related factors triggers inflammatory responses, leading to processes like vasodilation, leukocyte infiltration, and tissue damage in inflammatory pathologies.

In cancer-associated cachexia, elevated TNF-α and IL-6 exacerbate muscle and fat loss by regulating multiple metabolic signaling pathways, which could be ameliorated by Z526's suppression of NF-κB ...

IL-37 has been identified as an anti-inflammatory factor that translocates into the nucleus and downregulates other pro-inflammatory cytokines [6]. Nevertheless, whether autophagy regulates ... We ...

Ang II enzyme-linked immunosorbent assay (ELISA) kit, Ang II polyclonal antibody, TNFα, IL-1β, and IL-6 were purchased from Ray Biotech (Guangzhou, China). rabbit anti-Phospho-NF-κB-p65 (Ser536) and ...

HeLa cells express all core components of the NF-κB pathway and have a fully functional IL-1 system (Weiterer et al, 2020). They represent one of the most widely used cellular models to date (Adey et ...