Scientists at the Faculty of Medicine at the University of Freiburg have now shown that a sudden stop in energy production in mitochondria prevents normal cell death or so-called apoptosis and ...
The researchers confirmed that the increased production of hydrogen peroxide did not impede the function of mitochondria. They investigated a form of apoptosis caused by hydroxy radicals formed in the ...
Our findings demonstrate that mitochondria dynamics do not regulate apoptosis activation in C. elegans and reveal distinct roles for drp-1 and fis-2 as mediators of cell-death execution downstream of ...
Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen ...
Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death.
Apoptosis Inducing Factor (AIF) translocates from the mitochondria to the nucleus in cells undergoing apoptosis where AIF fragments DNA. This translocation can be measured by fluorescently labelling ...