As gene expression profiling reaches a plateau and begins to face limitations, miRNA signature is a rising star that may provide new resolutions to old problems. It is difficult to say whether ...

complicating comparison of microRNA amounts in a sample. Figure 2: DGE profiling analysis of a synthetic RNA pool. To determine whether DGE profiling allows for differential expression analysis ...

The tiny strings of RNA promote translation of a protein implicated in cancer ... (the process by which sugary molecules are stuck onto proteins), they weren’t expecting to find any ramping up gene ...

MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post transcriptional level. They are known to play a critical role in multiple biological ...

Thermo Fisher Scientific, Horizon Discovery, OriGene Technologies, QIAGEN, and GeneCopoeia Lead the Competition MicroRNA ...

The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi ... 1 Scientists have harnessed RNAi in the laboratory to ...

There are notable differences between men and women in their susceptibility to many human diseases, including cardiovascular ...

miRNAs are important negative gene regulators that have critical roles ... The evaluated study examined the miRNA profiles in peripheral blood mononuclear cells from PDAC patients.

You can gain deeper understanding of expression patterns of small non-coding RNAs by using assays that retain spatial organization at single cell resolution. Traditional methods such as NGS, can ...

His team analyzed literature on miRNA, summarizing the close relationship ... Almost all known cancer cells have the ability ...

“What excites us most about this discovery is that it indicates plants may control their microbiomes, in part, by regulating gene expression in microbes using cross-kingdom RNA ...