With every bite of food we take, our intestinal immune system must make a big decision. Tasked with defending us from foreign ...

Now, researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have analyzed the entire mouse intestine, mapping gene expression and cell states and location in the ...

The studies were carried out in genetically modified mice and intestinal organoids from mice and humans—self-organized three-dimensional tissues derived from stem cells in the intestine.

Food allergies can be life-threatening due to the rapid and exaggerated immune response. While mucosal mast cells (MMCs) are ...

Maternal microbiome-derived metabolites during pregnancy impact offspring stem cell function, offering potential therapeutic ...

Excessive sugar consumption is linked to several non-communicable diseases, including obesity, cardiovascular disease, metabolic syndrome, and type 2 diabetes.

Researchers have pinpointed an intestinal protein that influences gut microbes, causing the body to become intolerant to ...

Intestinal fibrosis, as a late-stage complication of inflammatory bowel disease (IBD), leads to bowel obstruction and requires surgical intervention, significantly lowering the quality of life of ...