Autophagic death is attenuated by chemokines in circulation, surviving signaling and possibly other mechanisms ... support their mitogenic activity. Metastasis Formation by Disseminated Tumor ...

A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and ...

However, their role in the destruction of bone in melanoma metastasis remains unclear. Understanding the molecular mechanisms driving osteocyte death is crucial to developing effective treatments ...

But new research suggests an alternative mechanism has been overlooked—elusive mutations driving metastasis may not be developing within the twisted DNA of tumors themselves, but within the ...

A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...

As I learned more about it, I realized that ovarian cancer has a unique and interesting mechanism of metastasis, which stimulated me to keep investigating it. What did you focus on when you first ...

A recent study by researchers at IRB Barcelona has identified a fatty acid found in palm oil, called palmitic acid, as a significant promoter of cancer metastasis in oral cancer and melanoma. Unlike ...

very high concentrations in the lungs of mice with metastatic breast cancer. Many proteins in our bodies can affect the translation process, among them the so-called initiation factors.

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation ...

Epidermal growth factor receptor (EGFR) is a major driver of cancer dissemination and target for anti-cancer therapies but ...

they are critical steps in the metastatic process that impose significant selective pressure on tumor cells. Therefore, the mechanisms employed during these early stages of metastasis are ...