Autophagic death is attenuated by chemokines in circulation, surviving signaling and possibly other mechanisms ... support their mitogenic activity. Metastasis Formation by Disseminated Tumor ...

they are critical steps in the metastatic process that impose significant selective pressure on tumor cells. Therefore, the mechanisms employed during these early stages of metastasis are ...

While medicine has made great progress in treating primary tumors, it is still largely helpless in the face of metastasis.

However, their role in the destruction of bone in melanoma metastasis remains unclear. Understanding the molecular mechanisms driving osteocyte death is crucial to developing effective treatments ...

Ultimately, this evasion mechanism enables some DCCs to "wake up" from dormancy and reactivate to form metastases. "Understanding how immune cells keep DCCs in check could lead to new anti ...

A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...

1 The fact that ovarian cancer is such a pressing clinical problem motivates us to study it. As I learned more about it, I realized that ovarian cancer has a unique and interesting mechanism of ...

A recent study by researchers at IRB Barcelona has identified a fatty acid found in palm oil, called palmitic acid, as a significant promoter of cancer metastasis in oral cancer and melanoma. Unlike ...

More recently, work led by Dr. Massagué has identified genes and mechanisms that promote cancer metastasis to the bone, lung, and brain in a number of cancer types. This research has illuminated the ...

very high concentrations in the lungs of mice with metastatic breast cancer. Many proteins in our bodies can affect the translation process, among them the so-called initiation factors.