The cancer microenvironment, or tumour microenvironment, describes the non-cancerous cells present in the tumour. These include fibroblasts, immune cells and cells that comprise the blood vessels.

An international team of UK and US scientists has discovered that the activity of macrophages—a type of white blood cell that ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

Finding ways to tackle tumour associated macrophages, part of the “tumour microenvironment” that ... This will involve moving its first cancer drug into clinical trials, and starting work ...

An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Cancer development and ...

The pro-inflammatory M1 macrophages and inflammation-related ... of new targeted therapies that precisely influence the tumor microenvironment and immune cell interactions, ultimately leading ...

to target tumor-associated macrophages (TAMs), thus enabling precise spatiotemporal siRNA delivery. This system enhances the tumor microenvironment and supports precise photoimmunotherapy.

Discover how immune iFRET biomarkers offer new insights into predicting response to neoadjuvant melanoma therapy, driving ...

“Our findings demonstrate that CAR-NKT cells not only effectively eliminate CD1d-expressing M2-like macrophages within the tumor microenvironment but also stimulate endogenous immune cells ...

Further research into the different injury models at different time points showed that the microenvironment of the lung caused subtle changes in protein expression and macrophage survival.