The duo were the first researchers to identify the disease-specific reprogramming of macrophages in cancer. TAMs are the most abundant immune cell in many types of cancer and modulating their ...
Carisma Therapeutics is developing a unique, differentiated immuno-oncology (IO) treatment for solid tumors based on chimeric antigen receptor macrophages (CAR-M). Current IO treatments have ...
They found that T cell presence showed no consistent trends to viral stimulation or tumor response before and after the treatment, but there was a heavy infiltration of macrophages after treatment ...
This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...
A research team has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod.