Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Using fate-mapping techniques, we and others demonstrated that the intestine also harbours self-maintaining macrophages that reside in specific anatomical locations within the intestinal wall. These ...

The sites at which the macrophages initiated phagocytosis of myelin might be associated with the location of complement deposition in certain patients with AIDP. Contributors HK and GS developed the ...

Pro-inflammatory macrophage activation is a hallmark example of how mitochondria serve as signaling organelles. Oxidative phosphorylation sharply decreases upon classical macrophage activation, as ...