New findings from the VIB-UGent Center for Inflammation Research reveal that macrophage activation states are crucial for liver repair following injury. The study, led by Prof. Charlotte Scott and her ...

Exosomes from non-HCC sources also modulate the TIME: M1 Macrophage-Derived Exosomes: These vesicles exhibit anti-tumor properties by delivering miRNAs that inhibit oncogenic pathways in HCC cells.

More importantly, they identified specific macrophage subpopulations that are critical for resolving MASH and liver fibrosis ...