Macrophage activation syndrome (MAS) is a rare disease characterised by aberrant immune hyperactivation of T lymphocytes and macrophages driven by cytokine dysfunction. The HLH-2004 protocol is ...

Macrophage activation syndrome is caused by excessive activation and proliferation of T cells and macrophages, which leads to an overwhelming and potentially fatal inflammatory reaction.

Objectives Macrophage activation syndrome (MAS) is a severe, life-threatening complication of systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still’s disease (AOSD). The objective of ...

Secondary HLH occurs in the setting of a malignant, infectious or autoimmune stimulus. Macrophage activation syndrome (MAS) is the term used to describe HLH that develops secondary to rheumatological ...

That’s how doctors describe macrophage activation syndrome (MAS) – an uncommon but potentially life-threatening complication of systemic juvenile idiopathic arthritis (SJIA). Although it can occur ...

A significant complication associated with AOSD is Macrophage Activation Syndrome (MAS), a severe inflammatory condition that can occur in patients with AOSD, leading to life-threatening ...

Objective To identify which laboratory tests that change over time are most valuable for the timely diagnosis of macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic ...

The morbidity and mortality rises further due to an underlying immuno-modulatory process presenting as MAS (Macrophage Activation Syndrome) than accompanies the state of sepsis. Objectives To describe ...

Background Adult-onset Still’s disease (AOSD) is associated with the development of macrophage activation syndrome (MAS) [1], sometimes termed secondary haemophagocytic lymphohistiocytosis (sHLH), a ...

H emophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) are life-threatening systemic hyperinflammatory syndromes. Systemic hyperinflammation and HLH/MAS can occur in ...