In animal models, inhibition of neutrophil chemokines or disruption of these chemokine gradients in the lung attenuates ALI. Molecules associated with enhanced wound closure, such as epithelial ...

spread cell-death signals to their surroundings and increase tissue damage. Mechanistically, ferric ammonium citrate (FAC) activates lipid peroxidation in primary lung epithelial cells ...

The new therapeutic concept is based on blocking FasL and to thereby prevent the untoward death of T cells and lung epithelial cells and the inflammation resulting therefrom. The academic members ...