LSD1 is thought to play a role in the maturation of blood cells in the bone marrow and acts as a driver for certain blood cancers. Merck has traditionally eschewed large-scale M&A, but has been ...
The two new compounds – LSD1 inhibitor EXS74539 and MALT1 protease ... as the protein is thought to regulate gene expression in bone marrow stem cells. It is found at elevated levels in a ...