为解决 NACT 对乳腺癌患者外周单核细胞影响及预后贡献不明的问题,亚历山大大学研究人员开展相关研究。结果发现 NACT 影响 CD14+CD16 + 单核细胞和 sCD163 水平,且二者与临床反应有关。该研究为乳腺癌治疗提供新思路,值得一读。 埃及亚历山大大学医学研究所 ...
LPS receptor-deleted mice (i.e., CD14 mutants) are hypersensitive to insulin, and the occurrence of insulin resistance, obesity, and diabetes is delayed in response to high-fat feeding.
Furthermore, liver, but not whole-body, insulin resistance was detected in LPS-infused mice. CD14 mutant mice resisted most of the LPS and high-fat diet-induced features of metabolic diseases.