The etiology of IBD, however, is unclear but believed to involve an excessive immune response. Epithelial cells that line the inner layer of the intestine tract supply a barrier for entrance of ...

epithelial layer), humoral elements (defensins, IgA), immununological elements (lymphocytes, innate immune cells), muscular and neurological elements Intestinal permeability is defined as a ...

In vivo, the intestinal epithelium interacts with the neighboring environment through complex crosstalk, which involves components such as the immune system, tissue microenvironment, and gut microbes.

Researchers report the ability of tofacitinib to reduce infection risk with SARS-CoV-2 in individuals who are deficient in PTPN2.

Peyer's patches as immune hubs: Peyer’s patches in the small intestine are crucial ... Microfold (M) cells are a specialized ...

The stress of heat and oxidative damage during exercise causes disruption to intestinal epithelial cell tight junction proteins resulting in increased permeability to luminal endotoxins. The endotoxin ...

The intestine is continually exposed to challenges from the diet, commensal microbiota or infectious microbes. As a result, the gut is also host to a complex network of immune cells that work together ...

In order to increase the complexity of this human biomimetic model, we are integrating engineered platforms that incorporate mechanoinduction, immune and neuronal cells ... doi: ...