Perhaps if we could work out the evolutionary history of innate and adaptive immunity, this could help us to understand the intricacies of how our immune system functions and sometimes dysfunctions.

This can involve, for example, macrophages and innate lymphoid cells. Their interaction with the adaptive immune system through myeloid-derived suppressor cells have also highlighted roles in ...

Innate immune cells exhibit rapid cytotoxic activity against foreign pathogens and malignant cells, and they have the capacity to launch a counterpart arm, the adaptive immune system. The T-cells ...

Many of the cells in the innate immune system produce cytokines or interact with other cells directly to activate the adaptive immune system. In cancer cells, mutations can lead to expression of tumor ...

If NK cells are indeed a “bridge” between innate and adaptive immunity, they might possess certain attributes of both. We now have evidence that several hallmark characteristics of the adaptive immune ...

How chronic activation of the innate immune system can lead to cancer The newer paper, led by first author Hexiao Wang, Ph.D.

Antibodies are a vital part of the immune system, playing a key role in our ability to fight infection and in the efficacy of vaccinations. However, that’s not where their utility ends. Find out about ...

The pervasive influence of the immune system on human health and disease underscores the importance of a mechanistic understanding of immune regulation under pathophysiological conditions such as ...

These exposures do not only include factors that impact adaptive immune memory, but also agents that shape innate immune responses for prolonged periods of time, moulding susceptibility to chronic ...