Now, the team have produced over 3 kilograms of racemic ibuprofen-nicotinamide co-crystals, pioneering the use of this green technique for large-scale synthesis. Ibuprofen is a ubiquitous pain ...

The precise mechanism of the analgesic properties ... of cyclooxygenase (COX-1 and COX-2). Because ibuprofen is also an inhibitor of prostaglandin synthesis, its mode of action may be due to ...