As a nonsteroidal anti-inflammatory drug (NSAID), ibuprofen's mechanism of action involves inhibiting the production of prostaglandins, chemicals in the body that play a pivotal role in triggering ...
All NSAIDs variably inhibit COX-1 and COX-2 and the mechanisms of inhibition fall ... reversible binding of COX-1 and COX-2 (e.g., ibuprofen, piroxicam, mefenamic acid); Category 2: rapid, lower ...
The precise mechanism of the analgesic properties ... of cyclooxygenase (COX-1 and COX-2). Because ibuprofen is also an inhibitor of prostaglandin synthesis, its mode of action may be due to ...