In this article we give an overview of RNA-based HPV diagnostics and the role of E6/E7 mRNA detection as a predictive marker for the development of cervical carcinoma. HPV E6/E7 mRNA testing for ...

An investigational therapeutic vaccine showed clinical effectiveness in patients with human papillomavirus (HPV)16-positive ...

Three studies were published last month by different research groups all focusing on the E6 and E7 human papillomavirus (HPV) proteins and their role in cervical cancer development. They reveal that ...

and the viral oncogene products E6 and E7. A complementary DNA (cDNA) of the antigenic L1 is used in HPV vaccine development involving viruslike particle technology. The E2 product prevents ...

A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical ...

Clinical trials that have been done up to now have been moderately successful in eliciting cell-mediated immune responses to HPV E6 and E7 in patients with a spectrum of HPV-associated disease.

A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical lesions, according to the results from a phase II clinical trial published ...

L2是一种小分子蛋白质，它在病毒感染细胞时起到关键作用。E6和E7则是大分子蛋白质，它们参与调节细胞周期并促进癌变的发生。 HPV病毒可以通过性接触传播，并且可以引起多种类型的癌症 ...

凯普生物10月13日公告，全资子公司高危型人乳头状瘤病毒E6/E7区mRNA检测试剂盒(PCR-荧光探针法)取得医疗器械注册证书。 该 ...

Gen-Probe is currently developing the APTIMA HPV Assay, targeting E6/E7 mRNA from 14 carcinogenic HPV genotypes. A prototype of this assay was evaluated recently in 536 women with histological ...

A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical lesions, according to the results from a phase II clinical trial.