Abstract: Affinity maturation of antibodies during immune responses is achieved by multiple rounds of somatic hypermutation and subsequent preferential selection of those B cells that express ... with ...

Prognostic impact of immunohistochemically defined germinal center phenotype in diffuse large B-cell lymphoma patients treated with immunochemotherapy. Blood 109 , 4930–4935 (2007). Article CAS ...

In this manuscript, Hoon Cho et al. presents a novel investigation into the role of PexRAP, an intermediary in ether lipid biosynthesis, in B cell function, particularly during the Germinal Center (GC ...

This study provides useful insights into the ways in which germinal center B cell metabolism, particularly lipid metabolism, affects cellular responses. The authors use sophisticated mouse models to ...

Germinal center (GC) activation is limited due to poorly developed follicular dendritic ... and biotinylated peanut agglutinin (PNA)-bio (Vector Laboratories, Burlingame, CA) to label dark-zone B ...