This includes transcription, biogenesis ... to both mitotic and meiotic cell divisions. The classical epigenetic mechanisms include DNA methylation and histone modifications, but other mechanisms ...

Epigenetics is the study of various heritable alterations that control ... One function of histone modifications is to make DNA more or less accessible for transcription. Heterochromatin is highly ...

The Whitehouse lab is broadly interested in understanding how chromatin functions in the regulation of cellular processes such as DNA replication, gene transcription and epigenetics. We focus on ...

During transcription, the DNA sequence of a gene is copied into a complementary RNA molecule called messenger RNA (mRNA). This process is carried out by the enzyme RNA polymerase, which binds to the ...

He discovered both DNA and epigenetics can play a huge role in outcomes. And now he’s porting it to Web3. “DNA provides the genetic blueprint we're born with, determining everything from our ...

Aging cells with weakened gene regulation spuriously transcribe RNAs ... normally seen at the start sites of transcription at sequences known as promoters and provides further support that epigenetic ...

Epigenetics, the study of changes in gene function that do not involve ... either by directly affecting transcription factors or by influencing their response to environmental changes.

This is where DNA and RNA epigenetics come in: a series of mechanisms that act as "markers" on genes, to control their activity without modifying the DNA or RNA sequence itself. Until now ...

We are multidisciplinary lab that combines computational biology, machine learning, AI and molecular biology to decode the contribution of epigenetics (DNA methylation and histone modifications), ...

Short-chain fatty acids (SCFAs) like propionate and butyrate are critical byproducts of dietary fiber digestion. These molecules do more than fuel the body—they directly influence gene expression and ...

The Epigenetics Research Innovation Lab (ERIL) has been established to contribute to the growing epigenetics research community at MSK and support efforts to define the epigenetic mechanisms that ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...