Their study reveals that specific cells, known as fibroblastic reticular cells (FRCs), create environments within tumors that help protect and activate immune cells to fight the cancer effectively.

Discover how specialized cells form immune-boosting niches in lung tumors, unlocking new strategies to enhance cancer treatments and improve outcomes. Study: Fibroblastic reticular cells generate ...

and fibroblastic reticular cells (FRC). Conversely, stromal cell-derived chemokines such as CXCL13 govern the positioning of T and B cells, establishing SLO structures with segregated zones ...

One significant area of research has been the role of fibroblastic reticular cells (FRCs) in maintaining lymph node structure and function. FRCs are essential for creating niches that support ...