In addition, they showed that treatment with R3Mab reduced the phosphorylation of FGFR substrate 2α and mitogen-activated protein kinase, indicating that FGFR3-mediated signalling was suppressed.
Fibroblast growth factor receptor 3 (FGFR3) is a protein in humans that is expressed in tissues including cartilage, and the brain, intestines, and kidneys. Driver or selfish mutations ...