Figure 1: Mechanisms of rapid non-genomic receptor-dependent actions of estrogen in four cell types. E2 induces MAPK phosphorylation and activation within 5 minutes in osteoblasts (ref.
CaP: Prostate cancer; DPN: Diarylpropionitrile; E: Estradiol 17b; ER: Estrogen receptor; GPR: G-protein-coupled receptor; MPP: Methyl-piperidino-pyrazole; PC ...
and it also blocks androgen receptors in the skin. Estrogen stimulates angiotensin synthesis and enhances aldosterone-mediated water and sodium retention, making it responsible for such unpleasant ...
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