Ephrin-B2 is required for the formation of ... receptors—thereby regulating VEGF-induced angiogenesis in normal and pathological conditions. Growth and development of normal tissues and tumors ...

EphrinB2 is also overexpressed in HCC, promoting angiogenesis and apoptosis inhibition, making it a potential target for anticancer therapies. In CCA, EphB2 and its ligands (ephrinB1 and ephrinB2) are ...

In this millenium, we will be required to answer such questions as: Will it be possible to treat ischemic heart disease by stimulating myocardial angiogenesis, and will it be feasible to cure ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

However, EGFR targeting therapies in gastric cancer show only marginal effects, and the molecular mechanisms of oncogenic EGFR signaling remain poorly defined. Here, we report Ephrin A1 as a novel ...