The successful and safe delivery of therapeutics relies on understanding how easily drugs can pass through biological barriers which protect cells.
New research has outlined guidance for using AI to help bridge the gap between in silico, in vivo and in vitro drug testing.
Passive diffusion and transporters coexist to affect drug disposition. Join Research Fellow Li Di of Pfizer during this free interactive broadcast as she discusses why design principles that increase ...
Monash University researchers have revealed how the gut—and what we eat—regulates high blood pressure, opening the door to ...
Understanding how bacteria control the entry and efflux of chemicals helps us to explain and possibly reverse antimicrobial drug resistance ... and increased efflux is referred to as “reduced ...
Applications of the concept of drug-likeness, which involve consideration ... candidates owing to issues such as poor solubility and permeability. Seeking to understand why, Christopher Lipinski ...
The gut and two cell regulators may pave the way to better high blood pressure drugs.Monash University researchers have revealed how the gut – and ...