perhaps by blocking the promoters at which activating transcription factors should bind. Presently, the exact role of methylation in gene expression is unknown, but it appears that proper DNA ...

Sen and her colleagues studied fragments containing cryptic sites and compared the levels of histone methylation, which winds up DNA and switches it “off” by making it unavailable for transcription, ...

Andrew Teschendorff, Professor at the Chinese Academy of Sciences, is developing computational systems-biological tools to ...

In NSC lineage progression, genes with increased methylation downstream of the transcription start site (TSS) showed reduced ...

while methylation at lysine residue K9 marked inactive chromatin. Heavily methylated regions of DNA with elevated concentrations of these so-called CpG groups are often found near transcription ...

Dunn, recently carried out a study exploring how DNA methylation, an epigenetic modification that entails the addition of a methyl group to the DNA, contributes to the well-documented relationship ...

“Today, when we don’t know what causes a disease, we say it’s likely epigenetic. In a sense, I think this epigenetic viewpoint is right, but we need much more evidence to get a defined picture.” Cedar ...

Dopamine, serotonin, and histamine carry messages between neurons. They can also influence circadian gene expression ...

DNA damage is a natural occurrence ... solid tumors and has also been identified as a transcription repressor. The role of this EZH2- mediated methylation is two-fold, the scientists discovered.

The methylation of plasma cell-free DNA (cfDNA) has emerged as a valuable diagnostic and prognostic biomarker in various cancers including colorectal cancer (CRC). Currently, there are no biomarkers ...

and methylation. One of the most important properties of guanine is its ability to form three hydrogen bonds with cytosine. This strong base pairing is crucial for the stability of the DNA double ...