Although still preliminary, the involvement of cytokine signalling loops in pre-malignant cell-fate decisions, as well as the defects in cytokine-receptor modules seen in later stages of cancer ...

Siltuximab effectively treated patients who experienced common adverse events after chimeric antigen receptor T-cell therapy, ...

Diseases such as covid-19 and influenza can be fatal due to an overreaction of the body’s immune system called a cytokine storm. Cytokines are small proteins released by many different cells in ...

With more cytokine-based drugs entering clinical trials and novel combination and masking technologies being used, there is a growing need for experts to discuss, understand, and build on the ...

But "mRNA really tells you about the ability to produce cytokines, rather than what's actually being produced," says Fred Finkelman of the University of Cincinnati. So many scientists measure cytokine ...

Basophils trigger a cytokine cascade that improves antitumor immunity in mice, offering potential targets for cancer ...

Defining hypercytokinemia Also called the ‘cytokine storm’, hypercytokinemia is a condition where too many cytokines are released. “They over-trigger the immune system. It’s like a war ...

Interim analysis of overall survival in potentially registrational phase 3 ARTISTRY-7 trial in platinum-resistant ovarian cancer expected in late ...

T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat ...

Patients with atopic dermatitis were at greater risk for serious infection after initiating Janus kinase inhibitors vs Th2 cytokine inhibitors.