Cyclin-dependent kinases (CDKs ... lack at least one of the conserved catalytic residues 2 and may not have kinase activity. Kinase activity has not been detected for several CDK-related proteins ...
Recent work has discovered the role of the cyclin-dependent kinase (CDK)-binding protein Cks1 in degrading the CDK inhibitor p27 Kip1. This process is essential for DNA replication and is ...