Pyro Q-CpG from Biotage gives a new dimension to DNA methylation studies by quantitatively measuring the individual degree of methylation of consecutive CpG sites consistently over time.

The methylation of plasma cell-free DNA (cfDNA) has emerged as a valuable diagnostic and prognostic biomarker in various cancers including colorectal cancer (CRC). Currently, there are no biomarkers ...

Thanks to these advancements, measuring DNA methylation at all CpG sites in the human genome is now possible. Since the technology can read lengthy DNA sequences, it is also possible to measure ...

This method reduces the cost and complexity of methylome analysis. With RRBS, scientists enrich for GC-rich parts of the genome by digesting the DNA with an enzyme that generates fragments with CpG ...

Dunn, recently carried out a study exploring how DNA methylation, an epigenetic modification that entails the addition of a methyl group to the DNA, contributes to the well-documented relationship ...

Edited by: Eugene Russo A. Merlo, J.G. Herman, L. Mao, D.J. Lee, E. Gabrielson, P.C. Burger, S.B. Baylin, D. Sidransky, "5´ CpG island methylation is associated with ...

In a nutshell Scientists discovered that random DNA mutations don’t just cause local damage, they trigger widespread changes ...

histone-deacetylating and methylation enzymes, CpG methyl-binding proteins, polycomb-silencing complexes) that target processes determining the recurrence or progression of events, and in what ...