The roles and targets of DNA methylation vary among the kingdoms of organisms. As previously noted, among Animalia, mammals tend to have fairly globally distributed CpG methylation patterns.

Pyro Q-CpG from Biotage gives a new dimension to DNA methylation studies by quantitatively measuring the individual degree of methylation of consecutive CpG sites consistently over time.

Epigenetic clocks that quantify rates of aging from DNA methylation patterns across the genome have emerged as a potential biomarker for risk of age-related diseases, like Alzheimer’s disease (AD), ...

With RRBS, scientists enrich for GC-rich parts of the genome by digesting the DNA with an enzyme that generates fragments with CpG dinucleotides at both ends, independent of methylation status. This ...

In a nutshell Scientists discovered that random DNA mutations don’t just cause local damage, they trigger widespread changes ...

Edited by: Eugene Russo A. Merlo, J.G. Herman, L. Mao, D.J. Lee, E. Gabrielson, P.C. Burger, S.B. Baylin, D. Sidransky, "5´ CpG island methylation is associated with ...

Thanks to these advancements, measuring DNA methylation at all CpG sites in the human genome is now possible. Since the technology can read lengthy DNA sequences, it is also possible to measure ...

Dunn, recently carried out a study exploring how DNA methylation, an epigenetic modification that entails the addition of a methyl group to the DNA, contributes to the well-documented relationship ...

histone-deacetylating and methylation enzymes, CpG methyl-binding proteins, polycomb-silencing complexes) that target processes determining the recurrence or progression of events, and in what ...