A blood smear revealed marked erythrocyte agglutination at room temperature (figure 1). The diagnosis of cold agglutinin disease (CAD) was confirmed with two cold agglutinin titers of 1/128 and 1/512, ...

Recordati is acquiring Sanofi’s Enjaymo, the only approved drug for the rare blood disorder cold agglutinin disease. Achieving sales milestones could bring the deal’s value to more than $1 ...

However, disease-causing genes have not been discovered, and familial cases have not been documented. 3 The presence of trisomy 3, trisomy 12, and translocation (8;22) has been reported in a few cases ...

The direct antiglobulin test was positive for anti-C3d specificity, with cold agglutinin titer confirming the diagnosis of CAD.

Cold agglutinin-mediated autoimmune haemolytic anaemia is associated with the development of autoantibodies that can agglutinate red blood cells at cold temperatures. While primary cold agglutinin ...

Sanofi has won FDA approval for its sutimlimab for cold agglutinin disease (CAD) at the second time of asking, becoming the first approved therapy for the rare blood disorder in the US.

Cold agglutinin disease (CAD ... In secondary CAD, the progression of the underlying disease can worsen CAD. If you develop lymphoma, its further advancement can lead to higher levels of cold-reacting ...