Cellular senescence, where cells permanently stop dividing, plays a complex role in liver health. In a recent review article, ...

衰老（Aging）是一种内在的生物学过程，其特征是系统性变化逐渐损害生理完整性，并增加患年龄相关疾病的风险，最终导致死亡。衰老的标志包括细胞衰老、基因组不稳定、表观遗传改变、蛋白稳态丧失、干细胞耗竭、慢性炎症以及细胞间通讯改变等。其中，细胞衰老（Ce ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological ...

Senescence is a process where cells cease dividing and undergo distinctive phenotypic changes. Senescence has a key role in the aging process and has also been implicated as a major cause of ...

Jan. 28, 2025 — The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been ... Keeping the Steps of Cell ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Study: Gut microbial-derived phenylacetylglutamine accelerates host cellular senescence. Image Credit: Tatiana Shepeleva / Shutterstock A recent study published in the journal Nature Aging ...

The Senescence Accelerated Mouse-Prone 8 (SAMP8) is a naturally occuring mouse line that displays a phenotype of accelerated aging. While maintaining an inbred AKR/J line in the early 1970's, ...