A new research perspective was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science) Volume 16, Issue 22 on December 9, 2024, entitled “Nuclear lipid ...

Cancer cells gobble up lipids. Prostate cells are stained with Oil-Red O to detect lipid droplets. Our work shows that redistribution of lipids from prostate cancer microenvironment triggers ...

But now, a study published in Nature demonstrates that one particular lipid type is actually critical for cancer immune evasion—so much so that certain cancer cells cannot proliferate without it.

Each cell is then encapsulated in a lipid droplet, together with a barcoded ... “Historically such experiments have been conducted using cancer cell lines, but we need to move to primary human ...

The Farese & Walther laboratory investigates cellular lipid and energy metabolism, in particular the mechanisms and physiology of neutral lipid synthesis and storage in lipid droplets. More broadly ...

Researchers discover novel targets for bladder cancer therapeutics and demonstrate that a new combination of existing drugs, including statins, blocks tumor growth in mice.

In both of these approaches, marine-derived lipids are used to selectively target components of the cancer cells or the tumor microenvironment. This addresses both the patient's overall health and ...

This enabled fast CAR T cell recovery and a mastery of "serial killing" of cancer cells. In contrast, researchers found that 4-1BB.ζ-CAR molecules linger in the lipid rafts and immune synapse. The ...