or prostaglandin E2 (PGE2) by monocytes stimulated by bacterial lipopolysaccharide (an index of COX-2 activity). Other assays are based on measurement of collagen-or arachidonic acid-induced ...
While COX-2 and its product, prostaglandin E2 (PGE2), are well-known for their involvement in inflammation and tumor growth, new research suggests that NSAIDs may also act through other pathways.