We show here active clustering of TCR–MHC molecules at the immune synapse after interaction between aAPC and T cells. This multivalent system allows identification and stimulation of antigen ...

How might the immune system take advantage of the B cell synapse to optimize the effectiveness of encounters between B cells and soluble toxin or circulating viruses? The answer may lie ...

The interaction between CD2 and CD58 is critical for forming the immunological synapse, which is pivotal ... axis can be exploited to activate CD28-CD8+ T-cells in cancer immunotherapy.