Regulatory B cells (Breg) or interleukin (IL)-10 producing B cells (B10) are also widely accepted as an important modulatory component of the immune system that suppresses T cell differentiation and ...

B-cell depletion with unconjugated CD20 monoclonal antibody (mAb) is used to treat rheumatoid arthritis and other autoimmune diseases. CD20-targeted immunotherapy depletes mature B cells through ...

Here, we elucidate specific properties of B regulatory cells in MS. These inconsistencies most likely arise from several Breg populations coexisting (55, 56). Indeed, these regulatory subpopulations ...

newcastle.ac.uk Objectives Tolerogenic dendritic cells (tolDCs) constitute a promising experimental treatment for targeting autoreactive T cells in autoimmune diseases, including rheumatoid arthritis ...

Rheumatoid arthritis (RA) is a complex condition that is well characterised by chronic inflammation ... much attention has been focused on the putative effects on the continuing inflammatory process ...

T-cell large granular lymphocytic (T-LGL) leukaemia is frequently associated with an autoimmune phenomenon; approximately one-third of patients have rheumatoid arthritis (RA). Intriguingly, one-third ...

Objectives Programmed cell death protein 1 (PD-1)-expressing T cells are implicated in the pathogenesis of autoimmune inflammatory diseases such as rheumatoid arthritis. A subset of CXCR5 − T cells, ...

[1] Pelissier A, Laragione T, Martinez MR, & Gulko PS. Cell-Specific Gene Networks and Drivers in Rheumatoid Arthritis Synovial Tissues (2023). bioRxiv (2023): 2023-12. [2] Pelissier A*, Laragione T*, ...

Obesity also involves patients with inflammatory arthritis. Knowing the impact of obesity on rheumatic diseases (rheumatoid arthritis, ankylosing spondylitis and psoriatic ... mediators predominantly ...