Fluorescent protein fusions have long been the go-to ... But the enzyme they were using, biotin ligase, was too specific for its small-molecule substrate, biotin, even after active-site mutagenesis.
Mapping the human E3 target protein landscape can help us understand ... label the ubiquitinated targets of a given E3 ligase with biotin directly inside cells. This allows the targets to be ...
And while you’re getting your biotin fix with a handful of mixed nuts, you’ll be reaping other benefits too—like their boost of protein and healthy fats. Almonds specifically are rich in ...
While manganese is an essential mineral involved in many bodily functions, both deficiency and excessive exposure can cause health issues.