A stable interaction between antigen-presenting cells (APC) and T cells is dependent not only on the absolute affinity between the T-cell receptor (TCR) and its ligand but also on the relative ...

To isolate immune cells, Lanna and his collaborators derived T cells and APC cells from the blood of human research participants, then cultured these cells. Then they exposed the cells to a mixture of ...

However, turning on stem cell genes in animals with mutant Apc caused the mutant cells to multiply and generate tumors. Preliminary results also suggest that high levels of HMGA1 may allow mutant ...