Competitive androgen receptor antagonists are used to treat prostate cancer but, even in the presence of such drugs, overexpression of androgen receptors can drive cellular proliferation ...
These included genetic models such as androgen receptor knockout mice and chronic androgen exposure in females using dihydrotestosterone (DHT) implants. Subsequently, they analyzed DNA from ...
A protein called the androgen receptor normally functions to guide the development of the prostate—signaling the cells to stop growing, act as normal prostate cells and maintain a healthy state.
The team has reported that androgen receptors are as important for sexual development and fertility in females as in males. Specifically, the researchers found that both male and female chickens ...
The researchers developed a detailed single-cell transcriptomic map from 17 different tissues ... Interestingly, ILC2s ...