Here, the authors identify the histone methyltransferase KMT2A as a binding partner of the PHF5A-PHF14-HMG20A-RAI1 protein subcomplex and an epigenetic regulator of the PCSCs characteristics and ...

In the study, published Jan. 8 in the journal Nature Communications, the mouse version of the protein, called STELLA, disrupted a key epigenetic factor and impaired tumor growth better than the ...

In the study, published in Nature Communications, the mouse version of the protein, called STELLA, disrupted a key epigenetic factor and impaired tumor growth better than the protein's human version.

Scientists say identification of two epigenetically different states in mouse model opens door to "entirely new world of ...

In the study, published Jan. 8 in the journal Nature Communications, the mouse version of the protein, called STELLA, disrupted a key epigenetic factor and impaired tumor growth better than the ...

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

Currently, epigenetic therapies are approved for blood cancers, such as leukemia, but not solid tumors. A prominent epigenetic target is UHRF1, a protein that is highly expressed in many solid tumors.

As well as being essential in the precise packaging of DNA into the space of the nucleus, histone proteins are also the site ...

This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...